Alpha-Synuclein NEALS Presentation

On Wednesday, November 2th, Dr. Smith's abstract regarding alpha-synuclein seed-amplification was presented at the NEALS convention in Clearwater, Florida.

The presentation was given by one of the authors, Dr. Robert Bowser and the poster that was presented is below.

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The lecture will be given in November at the Methodist Hospital (Houston). The invitation was extended by Dr. Stanley Appel, Chair of the Department of Neurology and Co-Director of the Methodist Neurological Institute.

This disappointing result was unexpected based on preclinical studies undertaken by Ionis Pharmaceuticals who, along with the Center, has championed the use of antisense therapeutics for treating neurologic disorders. Click here for more information.

Research undertaken by Dr. Smith on an antisense oligonucleotide clinical trial, published in Lancet Neurology in 2013, was referenced in an article in Science titled "RNA-targeted drugs for neuromuscular diseases" (Vol. 371, Issue 6524, pp. 29-31).